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Although in vitro studies in neonatal cells are lacking, numerous in vitro studies in adult cells showed that various immune cells fail to develop and function without adequate glutamine availability (146)

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* Nutrient reference value for daily intake (EU Regulation no

Further study showed that L-theanine could obviously increase the expression of Bcl-2 mRNA and protein, decrease the expression of Bax, a pro-apoptotic molecule, and decrease the phosphorylation of ERK1/2 and c-Jun NH2-terminal kinase (JNK1/2) MAPKs (87)

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