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The results are consistently positive and the mechanistic data is compelling, but as of 2026 there are no completed Phase 3 human randomized controlled trials

Food and Drug Administration (FDA) for any specific medical condition, and its use in humans is considered experimental

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Posted July 1, 2025 Reviewed by Hara Estroff Marano Key points Low levels of glutathione in the brain may be linked to mood and stress resilience

AOD-9604 enhances one component of energy balance (fat oxidation from adipose stores) without creating the negative energy balance that results from appetite suppression or the metabolic rate increases seen with thermogenic compounds

Those bad in melanin have a lighter skin tone