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and 5.14 kg and 1.89 kg/m 2 at 6 months [43]

Resultant oxidative DNA base lesions have the potential to mutate some genetic material, which would impair the integrity of the genome by preventing transcription and replication and by generating mutagenesis (116)

This is why some practitioners prefer it not just for multi-dose use but specifically because it's designed to remain chemically stable in a vial over an extended period

This is especially important for patients with absorption issues such as those with digestive conditions, low stomach acid (common with aging), or MTHFR gene variants who cannot adequately absorb B12 from food or oral supplements

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