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Li XT, et al

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635 As shown in Figure 12, 38% of Alzheimer's and other dementia caregivers indicate that the physical stress of caregiving is high to very high.A10 Dementia caregivers are 1.5 times more likely than nondementia caregivers to indicate substantial physical difficulty providing assistance to their care recipients

If the result is borderline or your symptoms are suggestive despite a "normal" number, MMA and homocysteine add diagnostic sensitivity

[1] [2] Some patients report reduced symptoms within weeks of starting treatment, whilst others may require several months of consistent supplementation before noticing significant improvement