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This research is funded by the scientific research project of the Youth Innovation Team Plan team of colleges and universities in Shandong Province (2022KJ257) and Shandong University of Chinese Medicine Lung Hidden Elephant Theory Research Young Scientific Research and Innovation Team (22202126)

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The primary weight-loss endpoint was not met

In vitro barrier models using Caco-2 cells (gut epithelium) or brain endothelial cells could be employed to test the hypothesis that microbiota metabolites, such as butyrateeither administered directly or derived from patient-derived fecal microbiota culturescan strengthen epithelial and endothelial barrier function and reduce oxidative stress [40]

Some of the familiar GAG compounds include glucosamine, heparan sulfate and chondroitin sulfate