Rejuvenation Res 10(2):157172 Kim J, Lee S, Choi BR, Yang H, Hwang Y, Park JHY, LaFerla FM, Han JS, Lee KW, Kim J (2017) Sulforaphane epigenetically enhances neuronal BDNF expression and TrkB signaling pathways
Supplemental studies have shed light on the upstream mechanism of this signaling pathway, demonstrating that sUA provokes IR in HUA by stimulating the Nuclear factor erythroid 2-related factor 2 (Nrf2)/Heme Oxygenase 1(HO-1) signaling pathway and upregulating the regulatory thioredoxin interacting protein (TXNIP), thereby inhibiting the IRS2/PI3K/AKT signaling pathway in macrophages (57)
[ In our study, we established a very strong positive correlation between mRNA levels of GCLc, GS, and GR on the one hand, and between GR and GS on the other
doi: 10.1089/ars.2010.3496 97 GhatiA.DamP.TasdemirD.KatiA.SellamiH.SezginG
Benefits of Oral Glutathione Skin Whitening and Brightening Glutathione reduces pigmentation, lightens scars, and evens out skin tone
10.1016/0014-5793(96)00332-8 56 Iturbe-OrmaetxeI.MatamorosM