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El-Shafei and Saleh (2016) found an insignificant change in serum creatinine level of DS-challenged rats

Stirban AO, Andjelkovic M, Heise T et al (2016) Aleglitazar, a dual peroxisome proliferator-activated receptor-alpha/gamma agonist, improves insulin sensitivity, glucose control and lipid levels in people with type 2 diabetes: findings from a randomized, double-blind trial

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We also report that 13% of patients with type 1 diabetes in our registry use adjuvant glucose-lowering therapy in addition to insulin, significantly higher than the 5.4% reported from the T1D Exchange Registry in the US [18]