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Nausea, constipation , and fatigue typically improve within 1-2 weeks at each dose level

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Another group independently also concluded that disability progression and brain atrophy occur earlier than in the classical secondary progressive stage, with many relapsing patients exhibiting insidious progression without clinical or radiographic evidence of inflammatory disease activity, coining the term silent progression (Cree et al., 2019)

Costs range from roughly $150 to $500 per month depending on the medication, source, and dose level

This is why it's particularly important during periods of rapid growth, such as pregnancy and childhood

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