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However, GIP immunoreactivity was identified in the adult rat brain using a specific monoclonal antibody against GIP (136), suggesting that while GIP is not expressed in the brain, peripheral GIP can reach the deep brain

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As demonstrated by MP0250 28 , the therapeutic protein's half-lives can be significantly extended by genetically fusing non-HSA-binding DARPins or other therapeutic proteins to albumin-binding DARPins