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Early Discoveries, With More to Come So far, GLP-1s, first approved 20 years ago for type 2 diabetes and later obesity, have shown potential in treating a surprisingly wide range of conditions, such as heart disease, Parkinsons, Alzheimers, sleep apnea, and liver disease

However, the RCT performance and outcomes are not always reflected in real-world studies, in part because of lower adherence and greater heterogeneity of population [90]

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Communicate with Your Doctor: If you have any concerns at all, talk to your prescribing physician or your pharmacist

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