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Furthermore, the high incidence of antibiotic resistance in Egypt poses a substantial barrier to the treatment and management of CAP [12]

Early IDD (radiographically mild degeneration or early symptomatic discs) is characterized by subtle bioenergetic stress with a mild decline in m and increased mitochondrial ROS (MitoROS), preceding overt cell loss and ECM collapse

This is normal tissue behaviour, not pathology

Monitoring duration and adjusting treatment as necessary is vital