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As such, the association with efficacy may be the result of enhanced trafficking of the protein within the cell that ultimately modulates the cell surface abundance of the receptor, rather than the result of alterations in the receptor protein structure that may influence ligand affinity

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The injection itself takes only a moment, and side effects are rare when appropriately administered

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The B12-carrier complex travels all the way down to the last section of the small intestine, the terminal ileum, where specific receptors absorb it into the bloodstream

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