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10.1038/s41420-025-02331-0 Cell Death Discov

In these trials, when assessing the efficacy and safety of gantenerumab ( 19 ) in participants with early (prodromal to mild) AD, the drug showed little clinical benefit in slowing cognitive decline, potentially due to limited clearance of amyloid plaques, with 5.0% participants experienced amyloid-related imaging abnormalities-effusion (ARIA-E) related side effects

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