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Justin Zaghi Last updated: July 27, 2024 Table of contents: About semaglutide How to get started 1

Following the first injection, expect less hunger and a suppressed appetite

2023;133:e169131

In rodents, intracerebroventricular (ICV) administration of the GLP-1R antagonist exendin-9 suppressed the effects of peripheral GLP-1R agonist administration (liraglutide and exenatide) on food intake reduction

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While standard high-dose protocols often cause vomiting and fluid loss, microdosing minimizes these side effects