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It appears in human plasma at approximately 200 ng/ml in young subjects, with a drop of more than 60 % between ages 20 and 60, an observation that motivated forty years of research on its role in tissue repair, wound healing, hair growth and cutaneous longevity

BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma

Construction and expression of recombinant uricase-expressing genetically engineered bacteria and its application in rat model of hyperuricemia