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Everyone in the study was overweight

Low-impact activities like walking, swimming, or yoga improve blood flow to sore muscles without placing excessive stress on them

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Beyond insulin effects, semaglutide slows gastric emptyingthe rate at which food moves from your stomachwhich extends satiety and reduces overall calorie intake without conscious restriction

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While not shown, this is most likely mediated by activation of GLP-1Rs in upstream CCK-expressing NTS neurons by exendin-4 since NE-expressing NTS neurons do not appreciably express GLP-1Rs [66]