Calcineurin is a transcription factor that is essential for the activation of nuclear factor of activated T-cells (NFAT), which is responsible for the production of pro-inflammatory cytokines, including IL-1, IL-2, IL-6, IL-4, and interferon (IFN)- (Pandey et al
These findings have generated interest in whether GLP-1-based therapies might benefit neurodegenerative conditions such as Alzheimer's disease
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