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The aim of this study was to compare the pain and functional outcomes of PRP with cortisone and placebo injections for the treatment of chronic plantar fasciitis

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doi: 10.1007/s10544-025-00755-0 71 SahliC.MoyaS

Long GV, Flaherty KT, Stroyakovskiy D, Gogas H, Levchenko E, de Braud F, Larkin J, Garbe C, Jouary T, Hauschild A, Chiarion-Sileni V, Lebbe C, Mandal M, Millward M, Arance A, Bondarenko I, JBAG H, Hansson J, Utikal J, Ferraresi V, Mohr P, Probachai V, Schadendorf D, Nathan P, Robert C, Ribas A, Davies MA , Lane SR, Legos JJ, Mookerjee B, Grob JJ

The new human data puts numbers to what clinicians were already observing anecdotally

Disulfide bonds remain stable in the extracellular environment but are cleaved in the reductive intracellular milieu, characterized by elevated glutathione levels, leading to liposomal destabilization and subsequent drug release