While this treatment isnt a cure for CFS, glutathione could help relieve symptoms and restore a better, more balanced quality of life
A 2010 study in Drug Metabolism and Disposition found that salidroside, one of rhodiola's primary bioactive glycosides, reduced CYP3A4-mediated testosterone 6-beta-hydroxylation activity in human liver microsomes 5
Hereditary defects in GSH synthetase are autosomal recessive and can lead to mental retardation and neuropsychiatric dysfunction in approximately 50% of patients, while this deficiency is routinely accompanied by metabolic acidosis and hemolytic anemia
PMID 21640828
It's a relatively high amount for a supplement to have, but it shouldn't be a problem for most people since the maximum per-day allowance for adults is 400mcg.34 That said, you may want to avoid Doctor's Best Glutathione + Milk Thistle if you take another supplement that includes selenium or eat a lot of selenium-rich foods (e.g., Brazil nuts, tuna)
selectively overexpressed SLC7A11 in the myocardium and found that it can increase cellular GSH levels and prevent FTH deficiency-mediated iron death [76]
