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In an effort to come to the rescue of that breed, in 1973 a very knowledgeable and courageous breeder, Dr

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The more physiologically relevant studies make use of in vivo transgenic mice, ex vivo perfused intestines or, more recently, crypt organoids derived from human, mouse or porcine guts (55)

It is considered an uncommon but well-documented reaction that is almost always mild to moderate

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