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GLP-1 drugs are prescription medications used to treat type 2 diabetes and obesity but carry serious side effects and must only be taken under the supervision of a qualified medical specialist, the ministry stated

A baseline physical examination should include: Resting heart rate and blood pressure (sitting and standing) Cardiac auscultation to detect murmurs or irregular rhythms Assessment for signs of heart failure (peripheral edema, jugular venous distension) Baseline electrocardiogram (ECG) should be considered for patients with known cardiovascular disease, cardiac symptoms, or history of arrhythmias, rather than routinely for all patients over a certain age

Intense demand for new diet drugs is changing food consumption

GLP-1 medicines in kidney and liver inflammation Treatment with an exenatide analog was found to significantly decrease hepatic lipid accumulation, liver weight, and plasma levels of alanine transaminase in mice on a high-trans-fat diet

Yabe D, Seino Y