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Because melasma is driven by chronic inflammation, calming these pathways is essential for preventing ongoing melanocyte overstimulation and recurrent discoloration

This is why Walshs approach emphasizes balancing methylationnot with folates, which can worsen symptoms in undermethylated individualsbut with nutrients that rebuild the methyl cycle naturally

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This phenomenon is observed in epilepsy patients, who experience neural hyperexcitation and an accelerated depletion of NSCs

But unlike 5-alpha-reductase inhibitors, GHK-Cu does not suppress DHT or compromise sexual function, making it a viable adjunct for anyone serious about optimizing both skin health and hair health