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doi: 10.1172/JCI112787 69 KanthakumarKTaylorGTsangKCundellDRutmanASmithSet al

A common titration approach includes: Week 12: 0.3 mg Week 34: 0.6 mg Week 56: 1.2 mg Week 78: 1.8 mg Week 9 and onward: 2.4 mg or higher, based on tolerance and clinical response Always consult a healthcare provider or licensed research facility for actual dosing guidance

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Failing to Plan for the Full Escalation Semaglutide trial protocols escalate from 0.25mg to 2.4mg weekly over several months

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