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For stubborn pigmentation or melasma, combining systemic antioxidant support (via the drip) with a targeted topical depigmentation treatment creates a two-pronged approach that addresses melanin production from both inside and outside

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The generation of ROS [322324] is often associated with DNA strand breaks induced by THC [315]

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Following 72 h of dialysis, the resulting solution was by using low-temperature freeze dryers, which yielded P4 (301 mg), presented as a brown powder