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The mechanisms by which estrogen promotes wound healing involve modulation of inflammation, oxidative stress, proteolysis, cell migration, proliferation, and angiogenesis, processes that were shown to be improved with the use of topical SERMs, estrogen precursors like DHEA, synthetic estrogens, and regenerative medicine approaches targeting estrogen signaling and biosynthesis

Gold Nanoparticles and Angiogenesis: Molecular Mechanisms and Biomedical Applications