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All tissues that use fatty acids as an energy source require carnitine for normal function during fatty acid oxidation

Associations have been shown between insulin resistance and elevated long-chain acyl-carnitines in the plasma [110,111], and patients with NAFLD have higher levels of long-chain acyl-carnitines [111]

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Controlled and uncontrolled studies using folinic acid, a reduced form of folate, have reported marked improvements in core and associated ASD symptoms in some children with ASD and folate related pathway abnormities

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