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Clinical manifestations range from asymptomatic elevations in serum transaminases to more severe conditions, including cholestatic jaundice, peliosis hepatis, hepatic adenomas, and, in rare cases, hepatocellular carcinoma (75)
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Incorporating the CSP-C4bp binding region into a CSP-based vaccine formulation could induce vaccine-mediated immunity that neutralizes this immune evasion region and increases the vaccine efficacy
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Reduce the appearance and smoothen pores