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Weekly morning weigh-ins, taken on the same day at the same time before eating or drinking, provide more reliable trend data
10) Lin GA, Lee W, Fahim SM, Richardson M, Phillips M, Raymond F, Rind DM
When we demand that New Approach Methodologies demonstrate "equivalent or better" performance, we must benchmark them against what animal studies actually deliver, not what we assume they deliver
Liver energy metabolism reprogramming: GLP-1RA reduces hepatic glucose output by decreasing hepatic FFA uptake and the expression of key gluconeogenesis enzymes such as PEPCK and G6Pase, while promoting liver sensitivity to insulin, transforming the liver from an "energy output organ" to an "energy storage organ"
PLoS One 2023
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