Ghrelin and desacyl-ghrelin stimulate hepatic steatosis through the direct activation of hepatocytes upregulating several transcription factors related to hepatic lipogenesis, such as PPAR, SREBF1 or CCAAT/enhancer-binding protein (C/EBP), as well as by upregulating key enzymes involved in triacylglycerol synthesis, such as monoacylglycerol O-acyltransferase 2 (MOGAT2) and diacylglycerol O-acyltransferase 1 (DGAT1) [107,108,109]
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GLP-1 For Seniors: A Safe and Practical Guide to Fat Loss While Protecting Strength and Mobility - Kindle edition by Theobald, Jason M
Cancer 19 , 625637 (2019)
I would say, What would you propose instead
Less muscle means a slower resting metabolic rate, which makes keeping weight off harder over time