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Research shows metabolic responses vary significantly based on genetic factors, baseline glucose regulation, and lipid profilesnot all patients experience identical outcomes

effects on clinical pregnancy and live birth rates were less consistent across treatments, although testosterone supplementation showed a statistically significant live-birth improvement (odds ratio 2.19, 95% CI 1.114.32)

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CKD was defined as having an eGFR less than 60 mL/min/1.73 m 2