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Studies have demonstrated that GLP-1RAs exert a direct effect on the heart and blood vessels (6) and an indirect effect via improved glycaemia (24), a reduction in blood pressure and postprandial rise in triglycerides (25), a reduction in markers of oxidative stress and systemic inflammation (26, 27) (Fig

Neurology 97(2):6879 Pemp B et al (2013) Effectiveness of averaging strategies to reduce variance in retinal nerve fibre layer thickness measurements using spectral-domain optical coherence tomography

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Monotherapy with the once weekly GLP-1 receptor agonist dulaglutide for 12 weeks in Japanese patients with type 2 diabetes: dose-dependent effects on glycaemic control in a randomised, double-blind, placebo-controlled study

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But the clinical conversation about lean muscle preservation is lagging behind the prescribing rate, and that gap has real consequences for patients, says Omar el-Gohary