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For individuals with type 2 diabetes, this can result in a significant reduction in HbA1c, a marker of long-term blood sugar levels

For topical formulations, concentrations of 0.1 to 0.3 percent are used, with efficacy detectable from as low as 0.01 percent

Hamilton adds that this can create a tired appearance, thin the skin and accentuate dark circles

doi: 10.1038/nature00887 97 WynneKBloomSR