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Weight gain is common due to metabolic changes and hypothyroidism

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Clinical trials have shown that tirzepatide effectively reduces HbA1c levels (1.24% to 2.58%) and body weight (5.4 kg to 11.7 kg) in type 2 diabetic patients, surpassing the effects of other agents

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We constructed standardized experimental models encompassing murine full-thickness burn injuries [13], rat dermal incisional wounds [13], and rodent skeletal muscle contusion models (Figure S1)