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Smits MM, Van Raalte DH

Lancet (1974) 2(7871):15

Recently, probiotics and prebiotics have been studied as treatments for dysbiosis

Insulin, IGF-1 and cancer Molecular pathways Insulin and the IGFs, IGF-1 and IGF-2, are structurally similar peptides with important roles in controlling metabolism and growth in response to nutrient signals and nutritional status

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This form forms a complex with CXCL12 to initiate leukocyte recruitment through CXCR4 interaction [49], while also activating the NF-B pathway through TLR2/4/9 to induce pro-inflammatory cytokine (IL-6, TNF-) secretion from monocytes