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PMID: 41903810 Toxicol Appl Pharmacol In silico and in vitro assessment of drugs potentially causing adverse effects by inhibiting CYP17A1

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This oxidative environment promotes NLRP3 inflammasome activation (a 1.8-fold increase in caspase-1 activity), establishing a self-perpetuating cycle of oxidative stress and inflammation (91)

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BPC-157 and TB-500 have shown favorable safety profiles in preclinical research, with few adverse effects reported