Based on the currently available, albeit limited data, efocipegtrutide (HM15211), another GLP-1/GIP/glucagon receptor triple agonist, seems to have beneficial effects in animal models of neurodegenerative diseases [67, 68]
Below 72 hours
This initially included Gus Watanabe, DiMarchii's close mentor and former Chief Scientific Officer at Eli Lilly (Molteni, Chen)
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The cardiovascular evidence is the most solid: in the SELECT trial, people with obesity and established heart disease who added semaglutide cut their risk of cardiovascular death, a second stroke, or a second heart attack by about 20%