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Because GLUT1 expression is downregulated with BBB degeneration, low levels of FDG in the BBB are indicative of BBB pathologies, and can identify AD and other dementias (Shivamurthy et al., 2015

This suggests that glutathione might protect against age-related diseases including cancer, diabetes, insulin resistance, and arthritis, which have been linked to high levels of oxidative stress

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A researcher in 2026 must choose: work on native peptides (ease of SPPS synthesis, abundant literature) or optimised mimetics (better pharmacokinetics, but complex synthesis, less literature)

Characterization of new potential anticancer drugs designed to overcome glutathione transferase mediated resistance