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This depends on how fast your body works, how much you use, and your habits

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The entry of oils and colloidal substances into the mixed bed is strictly prohibited, as these materials can clog the resin pores and are nearly impossible to remove completely through cleaning

Research Insight Repeated temperature fluctuations can often be more damaging than consistent refrigerated storage

However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing