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Our 2020 report highlighted that due to the failure of early anti-amyloid trials to achieve their intended outcomes, particularly studies involving BACE inhibitors and monoclonal antibodies, some have questioned whether amyloid remains clinically relevant in AD

Summary of efficacy and safety of currently-available obesity pharmacotherapy Tirzepatide and Emerging Approaches Besides the approval of semaglutide 2.4mg, much of the excitement in the field of obesity management also has to do with the approval of a dual GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist tirzepatide, which is currently approved for the management of T2D but has also shown promising results in the treatment of obesity in patients with and without T2D [28]

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Focus protein intake on b12-rich sources rather than plant-based proteins during active weight loss