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doi: 10.1007/s00299-018-2264-y 59

Importantly, weight loss with GLP-1 RAs has accompanied improvements in metabolic parameters and obesity-related comorbidities (e.g., glycemic control, lipid profiles, liver enzymes) in adolescents, mirroring findings in adults (see e.g., NASPGHAN and Endocrine guidelines)

Recombinant human insulin-like growth factor I stimulates growth and has distinct effects on organ size in hypophysectomized rats