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The cascade of events described (activation of proteases, generation of free radicals, and inflammation) after TBI results in cytoskeletal damage, death of glia and neurons, and white matter degeneration
Hence, the use of combination therapies to target multiple metabolic pathways to suppress tumor growth may be most effective, especially in identifying cases that induce synthetic lethality, where two drugs induce cell death in combination, but not individually
They are provided by a health care professional, such as a doctor, nurse, or nurse anesthetist
Berod L, et al