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This creates Reactive Oxygen Species (ROS) which generate more oxidative stress

Polyphenols, in particular, have attracted attention due to their antioxidant, anti-inflammatory, antiproliferative, proapoptotic, and gut-modulating properties 1

Second, comprehensive comorbidity indices (such as the Charlson comorbidity index), as well as structured data on smoking and alcohol consumption, were not systematically documented in the retrospective records and therefore could not be incorporated into the analysis

Extended half-life via acylation

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