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Analysis of blood parameters confirmed improvements in key markers of glucose and lipid metabolism, such as blood lipid levels, cholesterol, liver damage markers, and HOMA-IR

Patients who lose significant weight on semaglutide may need lower levothyroxine doses

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Proteomic signature of semaglutide treatment In STEP 1, statistical learning and feature selection were applied to derive a protein signature that distinguished participants receiving semaglutide from participants receiving placebo based on proteomic changes at end of treatment