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Steatoepatite metabolica (MASH) Solo semaglutide ha approvazione FDA Semaglutide ESSENCE (NEJM 2025) Tirzepatide SYNERGY-NASH (NEJM 2024) Verdetto: entrambi mostrano risultati istologici molto buoni nella MASH con fibrosi, ma solo la semaglutide ha ottenuto unapprovazione regolatoria (FDA, agosto 2025)

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It also appears to influence cell proliferation and modulate inflammation, with different molecular weights, such as LMW and HMW, exhibiting distinct biological activities

This is a significant development