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Although numerous preclinical studies have shown that iron chelators such as deferoxamine (DFO), deferiprone (DFP), and PBT2 effectively mitigate brain iron overload, reduce amyloid burden, and improve cognition in AD models, translation to the clinic has proven challenging

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Administration of Epitalon did not cause toxic effects at tested doses

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Longitudinal neuroimaging over 30 days: temporal characteristics of migraine