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Semaglutide, a GLP-1RA, mitigates seizure severity and cognitive impairment through the inhibition of the lipopolysaccharide (LPS)- and nigericin-induced NLRP3 inflammasome pathway, reducing lactate dehydrogenase (LDH) release by microglial cells [53]
Your provider can use biomarker assessment to differentiate these patterns and determine whether GLP-1 is appropriate given your specific health profile and lactation goals
New JAMA Study Links Wegovy to NAION A JAMA study published on July 3, 2024, on the Risk of Nonarteritic Anterior Ischemic Optic Neuropathy in Patients Prescribed Semaglutide found an increased risk of the condition in patients taking semaglutide compared to those taking non-GLP-1 RA medications
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When tirzepatide stops working or never worked well to begin with, exploring alternatives becomes necessary rather than optional
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