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2 Researchers have been able to show through many studies that GLP-1 indirectly works in the liver by inhibiting glucagon secretion by pancreatic alpha-cells, thereby inhibiting gluconeogenesis and glycogenolysis, thus decreasing hepatic glucose production

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Consistently, by ChIP assay, we detected significant NRF2 binding in Nqo1 and Slc7a11 loci, along with induced association of H3K4Me4 and H3K9Ac after DMF treatment (Fig