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These cytokines upregulate TfR1 and downregulate FTH1, thereby promoting intracellular iron overload and ROS generation, which directly sensitize NPCs to ferroptotic death (50)

Safety Profile and Cardiovascular Monitoring GLP-1 agonists show an excellent cardiovascular safety record in clinical trials, with cardiovascular events actually lower in treated groups than control groups

Compliance with the study drug, confirmed by vial count, was excellent at 98%

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