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Despite consistent patterns of SCFA depletion, the heterogeneity in microbial signatures across anxiety subtypes suggests disorder-specific pathophysiological mechanisms

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A responsible comparison should separate chemical stability from systemic bioavailability, distinguish drug uses from supplement positioning, avoid disease claims and evaluate molecular form, assay, impurities, dosage-form performance and current market-specific regulations

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Natural alternatives include DIY treatments with ingredients like lemon juice, honey, or oatmeal, though these tend to be milder and slower-acting

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