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One of the main effects of glutathione for skin is tyrosinase activity suppression, which slows down excessive melanin formation

4 The Lancet Cagrilintide phase 2 dose-findingLau DCW et al

The inhibition of somatostatin by DSIP has been found by a separate study, thus leading to the speculation that this peptide might have larger and more universal functions regarding human physiology than just primary sleep promotion, for which the direct inhibitory effects of somatostatin are more than peculiar

10.1038/s41591-018-0061-3 46 HsuC.-N.HouC.-Y.Chang-ChienG.-P.LinS.YangH.-W.TainY.-L

The superoxide radical, if not scavenged effectively, may directly inactivate several enzymes like CAT and GPx which are needed to eliminate hydrogen peroxide from intracellular medium [83]

Research has confirmed that the gut microbiota is a significant source of polyamine synthesis, with its production of putrescine, spermidine, and spermine playing a key role in maintaining intestinal polyamine homeostasis (83)